I love making this pepperoni bread because it’s a fun twist on pizza that’s perfect for sharing with friends or family. The combination of gooey cheese and spicy pepperoni wrapped in soft bread always feels like a little celebration. I can’t wait for you to try it and see how easy it is to make!
Most of the ingredients in this recipe are pretty common, but if you don’t usually keep frozen bread dough at home, you’ll want to pick that up at the supermarket. It’s usually found in the refrigerated or frozen section near other doughs or pizza crusts. The rest, like pepperoni, shredded mozzarella, olive oil, italian seasoning, and garlic powder, are easy to find in most grocery stores.
Ingredients For Pepperoni Bread Recipe
Frozen bread dough: This is the base of the bread and gives it a soft, chewy texture once baked.
Pepperoni slices: Adds a spicy, savory flavor that makes this bread taste like pizza.
Shredded mozzarella cheese: Melts perfectly to create a gooey, cheesy layer.
Olive oil: Brushed on top to help the bread brown nicely and add a little extra flavor.
Italian seasoning: A mix of herbs that gives the bread a classic Italian taste.
Garlic powder: Adds a subtle garlic flavor that complements the other ingredients.
Technique Tip for This Recipe
One of the trickiest parts of this Pepperoni Bread Recipe is rolling up the dough tightly without tearing it or letting the filling spill out. Here’s a simple way to do it step by step:
- After you’ve rolled out the dough into a rectangle and layered on the pepperoni and cheese, start rolling from one of the long sides.
- Use your fingers to gently lift the edge of the dough and begin to roll it over the filling.
- Keep the roll tight but don’t squeeze too hard or the dough might tear.
- Once you’ve rolled it all the way up, pinch the seams together firmly to seal the dough. This helps keep the pepperoni and cheese inside while baking.
- If you notice any small holes or tears, just press the dough back together or patch it with a little extra dough if you have some.
Doing this right makes the baking process smoother because the filling stays inside, so you get a nice, neat loaf that’s easy to slice. Plus, it helps the bread cook evenly and keeps all those yummy flavors locked in. If the dough isn’t sealed well, cheese might leak out and burn on the pan, which can make a mess and affect the taste.
When I first tried this, I rolled the dough too loosely, and the filling started to spill out while baking. It was a little messy, but I learned that pinching the seams tightly really helps. Also, brushing the top with olive oil before baking gives the bread a beautiful golden color and a little extra flavor, which I always look forward to. It’s a small step that makes a big difference!
Suggested Side Dishes
Alternative Ingredients
frozen bread dough - Substitute with pizza dough: Pizza dough offers a similar texture and can be easily rolled out and filled, making it a convenient alternative.
frozen bread dough - Substitute with homemade bread dough: Making your own dough allows for customization in flavor and texture, and it can be used just like frozen dough.
pepperoni slices - Substitute with salami slices: Salami has a similar spicy and savory profile, making it a good alternative for pepperoni.
pepperoni slices - Substitute with turkey pepperoni: For a lower-fat option, turkey pepperoni provides a similar taste with less grease.
shredded mozzarella cheese - Substitute with provolone cheese: Provolone melts well and offers a slightly sharper flavor, which complements the other ingredients.
shredded mozzarella cheese - Substitute with cheddar cheese: Cheddar adds a different flavor profile and a bit more sharpness, which can enhance the overall taste.
olive oil - Substitute with vegetable oil: Vegetable oil can be used in place of olive oil for a neutral flavor and similar cooking properties.
olive oil - Substitute with butter: Butter adds a rich flavor and can be used to brush the dough for a golden crust.
italian seasoning - Substitute with herbes de Provence: This blend includes similar herbs like thyme and oregano, providing a comparable flavor profile.
italian seasoning - Substitute with basil and oregano: Combining these two herbs can mimic the taste of Italian seasoning.
garlic powder - Substitute with fresh garlic: Fresh garlic provides a more intense and aromatic flavor, enhancing the dish.
garlic powder - Substitute with onion powder: While not identical, onion powder can add a savory depth in the absence of garlic.
Alternative Recipes Similar to This Bread
How to Store or Freeze This Bread
Allow the freshly baked pepperoni bread to cool completely on a wire rack. This ensures that any residual heat doesn't create unwanted condensation, which could make the bread soggy when stored.
Once cooled, wrap the pepperoni bread tightly in aluminum foil or plastic wrap. This helps maintain its freshness and prevents it from drying out.
For short-term storage, place the wrapped pepperoni bread in an airtight container or a resealable plastic bag. Store it at room temperature for up to 2 days. This method keeps the bread soft and flavorful, ready for a quick snack or meal.
If you wish to extend the life of your pepperoni bread, consider refrigerating it. Place the wrapped bread in the refrigerator, where it can stay fresh for up to a week. Remember, refrigeration might slightly alter the texture, making it a bit firmer.
For long-term storage, freezing is your best bet. Slice the pepperoni bread into individual portions before wrapping each slice in plastic wrap. This allows you to thaw only what you need, preserving the rest for future cravings.
After wrapping, place the slices in a freezer-safe bag or container. Label it with the date to keep track of its freshness. The pepperoni bread can be frozen for up to 3 months without losing its delightful taste.
When you're ready to enjoy your frozen pepperoni bread, remove the desired number of slices from the freezer. Let them thaw at room temperature or speed up the process by microwaving them for a few seconds.
To revive the crispy exterior, consider reheating the thawed slices in an oven preheated to 350°f (175°c) for about 5-10 minutes. This will restore the bread's golden-brown crust and melt the mozzarella cheese to gooey perfection.
If you prefer a softer texture, wrap the thawed slices in a damp paper towel and microwave them for 20-30 seconds. This method retains moisture, making the pepperoni bread soft and tender.
How to Reheat Leftovers
Preheat your oven to 350°F (175°C). Wrap the leftover pepperoni bread in aluminum foil to prevent it from drying out. Place it on a baking sheet and heat for about 10-15 minutes or until warmed through. This method helps maintain the bread's crispy crust and gooey mozzarella cheese interior.
Use a toaster oven for a quick reheat. Set it to 350°F (175°C) and place the pepperoni bread directly on the rack or on a small baking tray. Toast for about 8-10 minutes. This method is perfect for reheating a few slices while keeping the bread's texture intact.
For a speedy option, use the microwave. Place a damp paper towel over the pepperoni bread to add moisture and prevent it from becoming too chewy. Heat on medium power for 30-45 seconds. While this method is convenient, it may not preserve the bread's original crispiness.
If you have an air fryer, preheat it to 320°F (160°C). Place the pepperoni bread in the basket and heat for 5-7 minutes. The air fryer will help restore the bread's crispy exterior while ensuring the cheese melts perfectly.
For a stovetop method, use a skillet over medium-low heat. Place the pepperoni bread in the skillet and cover with a lid. Heat for about 5 minutes, flipping halfway through. This method helps achieve a nice, crispy bottom while warming the inside thoroughly.
Essential Tools for Making This Bread
Oven: Used to bake the pepperoni bread at the specified temperature until it is golden brown.
Rolling pin: Helps in rolling out the thawed bread dough into a rectangle on a lightly floured surface.
Floured surface: Provides a non-stick area to roll out the dough without it sticking.
Baking sheet: A flat surface to place the rolled dough seam-side down for baking.
Pastry brush: Used to brush olive oil over the top of the rolled dough before baking.
Measuring spoons: Ensures accurate measurement of olive oil, Italian seasoning, and garlic powder.
Knife: Used to slice the bread after it has cooled slightly.
Cooling rack: Allows the bread to cool slightly after baking to prevent it from becoming soggy.
How to Save Time on This Recipe
Prepare the filling: Pre-slice the pepperoni and pre-shred the mozzarella cheese to save time during assembly.
Thaw in advance: Thaw the frozen bread dough in the fridge overnight to ensure it's ready to use when you start cooking.
Use parchment paper: Line your baking sheet with parchment paper for easy cleanup and to prevent sticking.
Batch cooking: Double the recipe and freeze one loaf for a quick meal later.
Preheat the oven: Start preheating the oven while you assemble the bread to streamline the process.

Pepperoni Bread Recipe
Ingredients
Main Ingredients
- 1 loaf Frozen bread dough, thawed
- 1 cup Pepperoni slices
- 1 cup Shredded mozzarella cheese
- 1 tablespoon Olive oil
- 1 teaspoon Italian seasoning
- 1 teaspoon Garlic powder
Instructions
- Preheat your oven to 375°F (190°C).
- Roll out the thawed bread dough into a rectangle on a lightly floured surface.
- Layer the pepperoni slices evenly over the dough, leaving a small border around the edges.
- Sprinkle the shredded mozzarella cheese over the pepperoni.
- Roll up the dough tightly, starting from one of the long sides, and pinch the seams to seal.
- Place the rolled dough seam-side down on a greased baking sheet.
- Brush the top with olive oil and sprinkle with Italian seasoning and garlic powder.
- Bake for 25 minutes or until golden brown.
- Let it cool slightly before slicing and serving.
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